Applied Surrogate Endpoint Evaluation Methods with SAS and R (Chapman & Hall/CRC Biostatistics Series) - Hardcover

Alonso, Ariel; Bigirumurame, Theophile; Burzykowski, Tomasz; Buyse, Marc; Molenberghs, Geert; Muchene, Leacky; Perualila, Nolen Joy; Shkedy, Ziv; Van Der Elst, Wim

Hardcover

ISBN 10: 1482249367 ISBN 13: 9781482249361

Publisher: Chapman and Hall/CRC, 2016

Synopsis

An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

About this title

About the Author

Ariel Alonso, Theophile Bigirumurame, Tomasz Burzykowski, Marc Buyse, Geert Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv Shkedy, Wim Van der Elst

Edition details

• Publisher: Chapman and Hall/CRC
• Publication date: 2016
• Language: English
• ISBN 10: 1482249367
• ISBN 13: 9781482249361
• Binding: Hardcover
• Edition number: 1
• Number of pages: 374