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Heterogeneity in Asthma: 795 (Advances in Experimental Medicine and Biology, 795) - Hardcover
Book 31 of 490: Advances in Experimental Medicine and Biology
Synopsis
Asthma is a chronic relapsing airways disease that represents a major public health problem worldwide. Intermittent exacerbations are provoked by airway mucosal exposure to pro-inflammatory stimuli, with RNA viral infections or inhaled allergens representing the two most common precipitants. In this setting, inducible signaling pathways the airway mucosa play a central role in the initiation of airway inflammation through production of antimicrobial peptides (defensins), cytokines, chemokines and arachidonic acid metabolites that coordinate the complex processes of vascular permeability, cellular recruitment, mucous hyper-secretion, bronchial constriction and tissue remodeling. These signals also are responsible for leukocytic infiltration into the submucosa, T helper-lymphocyte skewing, and allergic sensitization. Currently, it is well appreciated that asthma is a heterogeneous in terms of onset, exacerbants, severity, and treatment response. Current asthma classification methods are largely descriptive and focus on a single aspect or dimension of the disease. An active area of investigation on how to collect, use and visualize multidimensional profiling in asthma. This book will overview multidimensional profiling strategies and visualization approaches for phenotyping asthma. As an outcome, this work will facilitate the understanding of disease etiology, prognosis and/or therapeutic intervention.
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Heterogeneity in Asthma (eng)
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Heterogeneity in Asthma
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Asthma is a chronic relapsing airways disease that represents a major public health problemworldwide. Intermittent exacerbations are provoked by airway mucosal exposureto pro-inflammatory stimuli, with RNA viral infections or inhaled allergens representingthe two most common precipitants. In this setting, inducible signaling pathwaysthe airway mucosa play a central role in the initiation of airway inflammationthrough production of antimicrobial peptides (defensins), cytokines, chemokinesand arachidonic acid metabolites that coordinate the complex processes ofvascular permeability, cellular recruitment, mucous hyper-secretion, bronchialconstriction and tissue remodeling. These signals also are responsible for leukocytic infiltration into thesubmucosa, T helper-lymphocyte skewing, and allergic sensitization. Currently, itis well appreciated that asthma is a heterogeneous in terms of onset,exacerbants, severity, and treatment response. Current asthma classification methods are largely descriptive and focuson a single aspect or dimension of the disease. An active area of investigation on how to collect, use and visualize multidimensionalprofiling in asthma. This book willoverview multidimensional profiling strategies and visualization approaches forphenotyping asthma. As an outcome, thiswork will facilitate the understanding of disease etiology, prognosis and/ortherapeutic intervention. 368 pp. Englisch. Seller Inventory # 9781461486022
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Heterogeneity in Asthma
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsIncludes cutting-edge methods and protocolsProvides ste. Seller Inventory # 4199733
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Heterogeneity in Asthma
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Condition: New. This book presents an overview on multidimensional profiling strategies and visualization approaches for phenotyping asthma. It includes cutting-edge methods and protocols and provides step-by-step detail essential for reproducible results. Editor(s): Brasier, Allan R. Series: Advances in Experimental Medicine and Biology. Num Pages: 368 pages, 8 black & white illustrations, 25 colour illustrations, biography. BIC Classification: MBGR; MFG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 754. . 2013. Hardback. . . . . Seller Inventory # V9781461486022
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Heterogeneity in Asthma
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Asthma is a chronic relapsing airways disease that represents a major public health problemworldwide. Intermittent exacerbations are provoked by airway mucosal exposureto pro-inflammatory stimuli, with RNA viral infections or inhaled allergens representingthe two most common precipitants. In this setting, inducible signaling pathwaysthe airway mucosa play a central role in the initiation of airway inflammationthrough production of antimicrobial peptides (defensins), cytokines, chemokinesand arachidonic acid metabolites that coordinate the complex processes ofvascular permeability, cellular recruitment, mucous hyper-secretion, bronchialconstriction and tissue remodeling. These signals also are responsible for leukocytic infiltration into thesubmucosa, T helper-lymphocyte skewing, and allergic sensitization. Currently, itis well appreciated that asthma is a heterogeneous in terms of onset,exacerbants, severity, and treatment response. Current asthma classification methods are largely descriptive and focuson a single aspect or dimension of the disease. An active area of investigation on how to collect, use and visualize multidimensionalprofiling in asthma. This book willoverview multidimensional profiling strategies and visualization approaches forphenotyping asthma. As an outcome, thiswork will facilitate the understanding of disease etiology, prognosis and/ortherapeutic intervention. Seller Inventory # 9781461486022
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Heterogeneity in Asthma
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Asthma is a chronic relapsing airways disease that represents a major public health problemworldwide. Intermittent exacerbations are provoked by airway mucosal exposureto pro-inflammatory stimuli, with RNA viral infections or inhaled allergens representingthe two most common precipitants. In this setting, inducible signaling pathwaysthe airway mucosa play a central role in the initiation of airway inflammationthrough production of antimicrobial peptides (defensins), cytokines, chemokinesand arachidonic acid metabolites that coordinate the complex processes ofvascular permeability, cellular recruitment, mucous hyper-secretion, bronchialconstriction and tissue remodeling.These signals also are responsible for leukocytic infiltration into thesubmucosa, T helper-lymphocyte skewing, and allergic sensitization.Currently, itis well appreciated that asthma is a heterogeneous in terms of onsetexacerbants, severity, and treatment response.Current asthma classification methods are largely descriptive and focuson a single aspect or dimension of the disease.An active area of investigation on how to collect, use and visualize multidimensionalprofiling in asthma. This book willoverview multidimensional profiling strategies and visualization approaches forphenotyping asthma. As an outcome, thiswork will facilitate the understanding of disease etiology, prognosis and/ortherapeutic intervention.¿Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 368 pp. Englisch. Seller Inventory # 9781461486022
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Heterogeneity in Asthma
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