Synopsis
Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.
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From the Back Cover
The pathophysiology underlying the relationship between obesity and cancer is complex and incompletely understood. Progression of certain cancers has been shown to accelerate in obese patients irrespective of their lifestyle and diet. Because obesity is manifested by overgrowth of white adipose tissue, it has been proposed that adipose tissue has a direct effect on cancer progression.
Adipose tissue is composed of several types of cells secreting numerous soluble factors collectively termed adipokines. In addition, infiltration of the immune system cells in obesity leads to increased production of a number of inflammatory factors by adipose tissue, thus contributing to the establishment of the metabolic syndrome. Endocrine signaling by adipose tissue-derived molecules has been shown to promote cancer in animal models, matching clinical associations. Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines.
This volume will discuss clinical and experimental data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.
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Adipose Tissue and Cancer.
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Adipose Tissue and Cancer
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Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression. Seller Inventory # 23676652/2
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Adipose Tissue and Cancer (eng)
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Adipose Tissue and Cancer
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Explores relationship between obesity and cancerExamines direct effect of adipose tissue on cancer Discusses role of endocrine signaling by adipose tissue-derived molecules in cancer promotionExplores relationship between obesity. Seller Inventory # 4199433
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Adipose Tissue and Cancer
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Springer New York Jul 2013, 2013
ISBN 10: 1461476593
ISBN 13: 9781461476597
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression. 200 pp. Englisch. Seller Inventory # 9781461476597
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Adipose Tissue and Cancer
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Springer New York, Springer US Jul 2013, 2013
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Buch. Condition: Neu. Neuware -Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 200 pp. Englisch. Seller Inventory # 9781461476597
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Adipose Tissue and Cancer
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Springer New York, Springer US, 2013
ISBN 10: 1461476593
ISBN 13: 9781461476597
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression. Seller Inventory # 9781461476597
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Adipose Tissue and Cancer
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Hardcover. Condition: Brand New. 1st edition. 190 pages. 9.25x6.25x0.75 inches. In Stock. Seller Inventory # x-1461476593