Excerpt from The Coagulation of Blood: Dissertation Submitted to the Board of University Studies of the Johns Hopkins University in Conformity With the Requirements for the Degree of Doctor of Philosophy
Recent investigators of the phenomenon of blood coagula tion have come to rather widely divergent conclusions. Morawitz(1) attempting to harmonize the older views of Schmidt, with the later work of Pekelharing, Hammarsten and others, gives four factors entering into the process. Three of these pre-exist in the circulating blood; the fibrinogen, the thrombogen or proferment, and the salts of calcium. The fourth factor arises at the moment of coagulation, and is produced by the disintegration of the formed elements of the blood-the platelets and probably also the leucocytes.
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Seller: Forgotten Books, London, United Kingdom
Paperback. Condition: New. Print on Demand. This book delves into the intricate mechanisms of blood coagulation, a crucial process in maintaining the integrity of the circulatory system. It begins by examining the historical understanding of coagulation, from Schmidt's early work to contemporary models involving multiple factors. The author meticulously dissects each factor, including fibrinogen, thrombin, and calcium, providing a comprehensive analysis of their roles in the coagulation cascade. Detailed experiments reveal the precise conditions under which thrombin exerts its action, as well as its stability and response to heat and pH changes. The book further investigates the enigmatic source of thrombin, exploring the theories of proferment activation and the involvement of formed blood elements. It also examines the potential role of tissue extracts and anti-thrombins, shedding light on their influence on coagulation dynamics. Ultimately, this book offers a refined and nuanced understanding of the complex interactions that orchestrate blood clotting, highlighting the delicate balance that ensures both hemostasis and the prevention of unwanted clots. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Seller Inventory # 9781334417900_0
Quantity: Over 20 available
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
PAP. Condition: New. New Book. Shipped from UK. Established seller since 2000. Seller Inventory # LW-9781334417900
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
PAP. Condition: New. New Book. Shipped from UK. Established seller since 2000. Seller Inventory # LW-9781334417900
Quantity: 15 available