Single-Molecule Science: From Super-Resolution Microscopy to DNA Mapping and Diagnostics - Hardcover

 
9781108423366: Single-Molecule Science: From Super-Resolution Microscopy to DNA Mapping and Diagnostics

Synopsis

Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachines, and protein folding and dynamics. A particular emphasis is also given to mapping DNA molecules for diagnostic purposes, and the study of gene expression. With numerous illustrations, this book reveals how SMS has presented us with a new way of understanding life processes. A must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, biological imaging, genomics and structural biology.

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About the Authors

Krishnarao Appasani is the Founder and Chief Executive Officer of GeneExpression Systems, a global conference-producing organisation focusing on biomedical and physical sciences. He is also an elected Life Fellow of the Royal Society of Biologists, London, UK.

Raghu Kiran Appasani is a Psychiatrist and Neuroscientist. He practices at University of Southern California. He is also the Founder and Chief Executive Officer of The MINDS Foundation.

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