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Synopsis
The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.
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About the Author
Bernhard O. Palsson is the Galletti Professor of Bioengineering and Professor of Pediatrics at the University of California, San Diego. For almost 30 years, his research has focused on the development of large-scale models of biological functions and their use to solve basic and applied problems in the life sciences. He has authored three previous textbooks.
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Systems Biology: Constraint-based Reconstruction and Analysis
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Cambridge University Press, 2015
ISBN 10: 1107038855
ISBN 13: 9781107038851
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Hardcover. Condition: Good. Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematical descriptions of the totality of these chemical interactions lead to genome-scale models that allow the computation of physiological functions. Reflecting these recent developments, this textbook explains how such quantitative and computable genotype-phenotype relationships are built using a genome-wide basis of information about the gene portfolio of a target organism. It describes how biological knowledge is assembled to reconstruct biochemical reaction networks, the formulation of computational models of biological functions, and how these models can be used to address key biological questions and enable predictive biology. Developed through extensive classroom use, the book is designed to provide students with a solid conceptual framework and an invaluable set of modeling tools and computational approaches. Seller Inventory # 404316
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Systems Biology : Constraint-Based Reconstruction and Analysis
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Cambridge University Press, 2015
ISBN 10: 1107038855
ISBN 13: 9781107038851
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Systems Biology : Constraint-based Reconstruction and Analysis
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SYSTEMS BIOLOGY
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Systems Biology: Constraint-based Reconstruction and Analysis
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Systems Biology: Constraint-based Reconstruction and Analysis
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ISBN 10: 1107038855
ISBN 13: 9781107038851
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Systems Biology: Constraint-Based Reconstruction and Analysis
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Systems Biology : Constraint-based Reconstruction and Analysis
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ISBN 10: 1107038855
ISBN 13: 9781107038851
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Systems Biology (Hardcover)
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ISBN 10: 1107038855
ISBN 13: 9781107038851
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Hardcover. Condition: new. Hardcover. Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematical descriptions of the totality of these chemical interactions lead to genome-scale models that allow the computation of physiological functions. Reflecting these recent developments, this textbook explains how such quantitative and computable genotype-phenotype relationships are built using a genome-wide basis of information about the gene portfolio of a target organism. It describes how biological knowledge is assembled to reconstruct biochemical reaction networks, the formulation of computational models of biological functions, and how these models can be used to address key biological questions and enable predictive biology. Developed through extensive classroom use, the book is designed to provide students with a solid conceptual framework and an invaluable set of modeling tools and computational approaches. Reflecting the latest developments, this textbook explains how quantitative and computable genotype-phenotype relationships can be built using a genome-wide basis of information about the gene portfolio of an organism. It has been developed through extensive classroom use, providing a conceptual framework in addition to invaluable modelling tools and computational approaches. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Seller Inventory # 9781107038851
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Systems Biology : Constraint-based Reconstruction and Analysis
Published by
Cambridge University Press, 2015
ISBN 10: 1107038855
ISBN 13: 9781107038851
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