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Patient-Derived Xenografts: Methods and Protocols: 2806 (Methods in Molecular Biology, 2806) - Softcover
Synopsis
This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with methodologies for generating PDXs from diverse clinical tissue samples as well as for utilizing PDXs in various specific cancer types. From the development of humanized PDX models to the exploration of protein expression through advanced techniques including multiplex immunohistochemistry, Western blotting, and immunoprecipitation, the chapters offer a comprehensive toolkit for researchers and clinicians alike. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Patient-Derived Xenografts: Methods and Protocols serves as an ideal interdisciplinary guide for understanding the intricate processes that underscore translational cancer research.
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This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with methodologies for generating PDXs from diverse clinical tissue samples as well as for utilizing PDXs in various specific cancer types. From the development of humanized PDX models to the exploration of protein expression through advanced techniques including multiplex immunohistochemistry, Western blotting, and immunoprecipitation, the chapters offer a comprehensive toolkit for researchers and clinicians alike. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Patient-Derived Xenografts: Methods and Protocols serves as an ideal interdisciplinary guide for understanding the intricate processes that underscore translational cancer research.
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Patient-Derived Xenografts
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ISBN 10: 1071638602
ISBN 13: 9781071638606
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Patient-Derived Xenografts : Methods and Protocols
Published by
Springer US, Springer US, 2025
ISBN 10: 1071638602
ISBN 13: 9781071638606
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Patient-Derived Xenografts
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ISBN 10: 1071638602
ISBN 13: 9781071638606
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with methodologies for generating PDXs from diverse clinical tissue samples as well as for utilizing PDXs in various specific cancer types. From the development of humanized PDX models to the exploration of protein expression through advanced techniques including multiplex immunohistochemistry, Western blotting, and immunoprecipitation, the chapters offer a comprehensive toolkit for researchers and clinicians alike. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch. Seller Inventory # 9781071638606
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Patient-Derived Xenografts: Methods and Protocols
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Patient-Derived Xenografts: Methods and Protocols
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Patient-Derived Xenografts: Methods and Protocols
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