Opsin-free Optogenetics: Technology and Applications (Methods in Signal Transduction Series) - Hardcover

Hardcover

ISBN 10: 1032249226 ISBN 13: 9781032249223

Publisher: CRC Press, 2022

Synopsis

Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools.

Key Features

• Describes new developments in non-opsin-based optogenetic tools
• Introduces cutting-edge methods for precise modulation of cell signaling
• Highlights applications of optogenetic regulation of cellular functions
• Covers contributions from an international team of leading experts

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About this title

About the Author

Yubin Zhou, Kai Zhang

Edition details

• Publisher: CRC Press
• Publication date: 2022
• Language: English
• ISBN 10: 1032249226
• ISBN 13: 9781032249223
• Binding: Hardcover
• Edition number: 1
• Number of pages: 186
• Editor: Zhou Yubin, Zhang Kai