Major advances are taking place in our ability to clarify the role of growth regulatory molecules, including those often referred to as growth factors, in the control of the generation of cell diversity, the proliferation of cells and in the specification of the overall patterns which determine embryological development and eventually produce the adult organism. The chapters of this volume illustrate the diversity of systems and the wide range of complementary experimental approaches that are playing a role in the elucidation of growth regulator structure, function and biology. The book deals not only with new techniques for exploring the functions of a very wide range of growth factors, modelling them in 3D and constructing families of related growth factors, it also covers the uses of recombinant DNA technology in the field and contains a section on the clinically relevant advances in the role of multifunctional growth factors in haemopoietic cells and the characterization of leukemia inhibiting factors.
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