Allogeneic Stem Cell Transplantation: Clinical Research and Practice (Current Clinical Oncology) - Hardcover

Hardcover

ISBN 10: 089603979X ISBN 13: 9780896039797

Publisher: Humana Press Inc., 2003

Synopsis

Internationally recognized physicians and researchers review both the basics of allogeneic stem cell transplantation and recent advances in the field, particularly as they relate to antitumor effects and graft-versus-host disease. They also provide unique decision-tree analyses to guide clinicians in selecting and managing their allogeneic transplant patients. The innovations discussed cover a variety of areas, ranging from stem cell mobilization in normal donors, to indications for allogeneic transplantation other than hematologic malignancies, to the use of nonmyeloablative conditioning regimens. The authors also explore new developments in the optimal selection of unrelated allogeneic grafts (e.g., matched unrelated donor, partially mismatched family member, or umbilical cord blood), the use allogeneic peripheral blood stem cell vs marrow-derived grafts for transplantation, and the kinetics of immune reconstitution after transplantation.

About this title

Review

From the reviews of the second edition:

“This authoritative book deals with all aspects of allogeneic hematopoietic stem cell transplantation (HSCT). … The book is directed at anyone working in the field of HSCT, whether clinician or researcher. It is detailed enough to provide in-depth information on several topics, and other topics are general enough to be useful to trainees in hematology/oncology … . this is a substantial book … . It compares very favorably with other works in the field and can be considered among the top on this subject.” (Jayesh Mehta, Doody’s Review Service, February, 2011)

From the Back Cover

Allogeneic transplantation has dramatically grown in importance as a curative cellular therapy for patients with hematologic malignancies and selected solid tumors, marrow failure disorders, and inherited metabolic diseases. In Allogeneic Stem Cell Transplantation: Clinical Research and Practice, internationally recognized physicians and researchers review both the basics of allogeneic stem cell transplantation and recent advances in the field, particularly as they relate to antitumor effects and graft-vs-host disease. They also provide unique decision-tree analyses to guide clinicians in selecting and managing their allogeneic transplant patients. The innovations discussed cover a variety of areas, ranging from stem cell mobilization in normal donors, to indications for allogeneic transplantation other than hematologic malignancies, to the use of non-myeloablative conditioning regimens. The authors also explore new developments in the optimal selection of unrelated allogeneic grafts (e.g., matched unrelated donor, partially mismatched family member, or umbilical cord blood), the use allogeneic peripheral blood stem cell vs marrow-derived grafts for transplantation, and the kinetics of immune reconstitution after transplantation.
Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice offers both clinicians and researchers concise advice on today's best clinical practice, as well as insightful analysis of the promising new lines of laboratory research that are leading to safer and more effective allogeneic transplant procedures.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2003
• Language: English
• ISBN 10: 089603979X
• ISBN 13: 9780896039797
• Binding: Hardcover
• Number of pages: 454
• Editor: Laughlin Mary J., Lazarus Hilliard M.