Tumor Models in Cancer Research (Cancer Drug Discovery and Development) - Hardcover

Hardcover

ISBN 10: 0896038874 ISBN 13: 9780896038875

Publisher: Humana Press Inc., 2001

Synopsis

Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in animal tumor model research. The wide array of models detailed form the basis for the selection of compounds and treatments that go into clinical testing of patients, and include syngeneic models, human tumor xenograft models, orthotopic models, metastatic models, transgenic models, and gene knockout models. Synthesizing many years experience with all the major in vivo models currently available for the study of malignant disease, "Tumor Models in Cancer Research" provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.

About this title

Review

"...the book synthesizes years of knowledge on all major models available for cancer research. As a first comprehensive summary on tumor models in many years, it is certainly a good reference to those working in preclinical and clinical cancer research and drug development." -Pharmaceutical Research "This publication belongs to the successful book series "Cancer Drug Discovery and Development™." The book provides an excellent guide over the experimental procedures developed in attempt to improve the treatment of malignancies. This publication represents an outstanding work devoted to the current state-of-the-art of the in vivo tumor models available for cancer research. The book will be of interest to oncologists, clinical and experimental cancer researchers. Practical approaches presented in the book, provide a guide to maximize the benefit for clinical anticancer treatment." - Neoplasma

From the Back Cover

Cancer researchers have made significant progress over the years by developing appropriate and accurate animal disease models, the most important being transplantable rodent tumors. In Tumor Models in Cancer Research, Beverly A. Teicher and a panel of leading experts comprehensively describe for the first time in many years the state-of-the-art in tumor model research. The wide array of model systems detailed form the basis for the selection of both compounds and treatments that go into clinical testing of patients, and include syngeneic, human tumor xenograft, orthotopic, metastatic, transgenic, and gene knockout models. These models represent the efforts of many investigators over the years and approach, with increasing precision, examples that serve as guides for the selection of agents and combinations for the treatment of human malignancy. Synthesizing many years of experience with all the major in vivo models currently available for the study of malignant disease, Tumor Models in Cancer Research provides preclinical and clinical cancer researchers alike with a comprehensive guide to the selection of these models, their effective use, and the optimal interpretation of their results.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2001
• Language: English
• ISBN 10: 0896038874
• ISBN 13: 9780896038875
• Binding: Hardcover
• Edition number: 2
• Number of pages: 708
• Editor: Teicher Beverly A.