DNA Damage and Repair: Advances from Phage to Humans (Contemporary Cancer Research) - Hardcover

Hardcover

ISBN 10: 0896038033 ISBN 13: 9780896038035

Publisher: Humana Press Inc., 2001

Synopsis

Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, and explains the important functional relationships among different DNA repair pathways and the relationship between DNA repair pathways, cancer etiology, and cancer therapies.

About this title

From the Back Cover

In recent years it has become increasingly apparent that DNA repair processes play key roles in protecting genome integrity, where the failure of repair systems is directly responsible for many, if not the majority of, cancers. In DNA Damage and Repair, Vol. III: Advances from Phage to Humans, Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eukaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. The contributors make every effort to integrate the basic experimental information with clinical aspects of cancer biology as they relate to DNA repair.
Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, offering broad integrated coverage that will help researchers understand the important functional relationships among different DNA repair pathways, as well as the relationships among DNA repair pathways, cancer etiology, and cancer therapies.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2001
• Language: English
• ISBN 10: 0896038033
• ISBN 13: 9780896038035
• Binding: Hardcover
• Number of pages: 426
• Editor: Nickoloff Jac A., Hoekstra Merl F.