Genomics Protocols: v. 175 (Methods in Molecular Biology) - Hardcover

Hardcover

ISBN 10: 0896037746 ISBN 13: 9780896037748

Publisher: Humana Press Inc., 2001

Synopsis

Expert researchers from academia, industry, and leading genome centers provide a comprehensive generic set of protocols for gene hunting and genome analysis. Drawing on emerging technologies in the fields of bioinformatics and proteomics, these protocols cover not only those traditionally recognized as genomics, but also early therapeutic approaches exploiting the potential of gene therapy. The highlights include methods for the analysis of differential gene expression, SNP detection, comparative genomic hybridization, and the functional analysis of genes, as well as the use of bioinformatics for gene identification and the prediction of protein function.

About this title

Review

"The two editors of this volume have invited contributors from a variety of authors to write a laboratory manual dealing exclusively with the application of genomic methods in eukaryotes....Each chapter is presented in a standardized fashion, beginning with an introduction followed by a list of all the materials needed (including the machines and software) a detailed experimental protocol, notes (troubleshooting), and a list of references....it will be of value for those requiring step-by-step "cookbook" procedures for some of the methodologies described, and this definitive and authorative volume belongs in the library of every quality research institution where genomics is performed." - CHEMBIOCHEM
.,."a solid introduction to the basic techniques involved in the process of disease gene identification...should prove to be useful to those scientists who wish to expand their skills in the field." -Biotech Software & Internet Report

From the Back Cover

Genome analysis is essential both to understanding the molecular bases of physiological processes and to the development of novel therapies for treating human diseases. In Genomics Protocols, an expert panel of internationally acclaimed researchers from academia, industry, and leading genome centers provides a comprehensive generic set of protocols for gene hunting and genome analysis. Drawing on emerging technologies in the fields of bioinformatics and proteomics, these protocols cover not only those traditionally recognized as genomics, but also early therapeutic approaches exploiting the potential of gene therapy. Highlights include methods for the analysis of differential gene expression, SNP detection, comparative genomic hybridization, and the functional analysis of genes, as well as the use of bioinformatics for gene identification and the prediction of protein function. Each method includes step-by-step instructions and invaluable notes that describe the quirks in a procedure and the little tricks that make all the difference to a successful outcome.
Comprehensive and eminently practical, Genomics Protocols provides academic and pharmaceutical researchers alike with richly detailed accounts of the most up-to-date genomics techniques, including the emerging technologies from proteomics-all highly effective tools that will help investigators expand their research horizons and better understand gene function.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2001
• Language: English
• ISBN 10: 0896037746
• ISBN 13: 9780896037748
• Binding: Hardcover
• Number of pages: 560
• Editor: Starkey Michael P., Elaswarapu Ramnath