Connexin Methods and Protocols: 154 (Methods in Molecular Biology, 154) - Hardcover

Hardcover

ISBN 10: 0896036588 ISBN 13: 9780896036581

Publisher: Humana Press Inc., 2000

Synopsis

Leading investigators describe in detail their best techniques to study the cellular and molecular biology of connexins, as well as physiological properties. These forefront methods are specifically designed to investigate the life of connexins from biosynthesis to assembly into gap junction channels, and also include powerful assays to perform functional studies on these routes of cell cell communication. Also discussed are the many specific theoretical aspects of connexin biology and physiology. Cutting-edge and highly practical, Connexin Methods and Protocols offers laboratory researchers a comprehensive collection of proven methods for studying the role of connexins in intercellular communication and human genetic disorders, as well as finding promising new therapeutics for those disorders.

About this title

From the Back Cover

An essential element in direct cell-cell communication between virtually all cell types in vertebrates, connexins have been recently linked to an increasing number of human genetic diseases. In Connexin Methods and Protocols, well established investigators describe in detail their best techniques for studying the cellular and molecular biology of connexins, as well as their physiological properties. These forefront methods are specifically designed to investigate the life of connexins from biosynthesis to assembly into gap junction channels, and also include powerful assays to perform functional studies on these routes of cell-cell communication. To ensure experimental success, each time-tested technique contains detailed step-by-step instructions, as well as tips on how to avoid pitfalls. Also discussed are the many specific
theoretical aspects of connexin biology and physiology.
Cutting-edge and highly practical, Connexin Methods and Protocols offers laboratory researchers a comprehensive collection of proven methods for studying the role of connexins in intercellular communication and human genetic disorders, as well as finding promising new therapeutics for those disorders.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2000
• Language: English
• ISBN 10: 0896036588
• ISBN 13: 9780896036581
• Binding: Hardcover
• Number of pages: 506
• Editor: Bruzzone Roberto, Giaume Christian