Neurotransmitter Transporters: Structure, Function, and Regulation - Hardcover

Reith, Maarten EA

Hardcover

ISBN 10: 0896033724 ISBN 13: 9780896033726

Publisher: Humana Press Inc., 2009

Synopsis

A comprehensive survey of recent advances made in characterizing neurotransmitter transporters - including their imaging in the living brain - and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2009
• Language: English
• ISBN 10: 0896033724
• ISBN 13: 9780896033726
• Binding: Hardcover
• Number of pages: 420