Recent advances in mental illness treatment illustrate the tremendous potential for medical progress through research. As a result, it has become imperative for the clinical researcher to be aware of the complex ethical issues surrounding medical research -- more than ever before. Written by recognized experts in the field, Ethics in Psychiatric Research provides a comprehensive overview of the ethical concerns and regulations covering medical research on human subjects. This practical manual presents the pros and cons of alternative approaches to consider for informed consent and other ethical issues related to clinical research into mental disorders. It examines methods for assessing and monitoring the quality of care during and after research. And it reviews how to effectively inform subjects of the risks and benefits of research. Ethics in Psychiatric Research discusses surrogate decision making and advance directives issues that arise when working with cognitively impaired research subjects. Covering of the special issues pertinent to conducting research with children and adolescents and people who abuse substances, the book includes an excellent chapter on patient and family concerns about research. Providing much-needed information for clinical investigators on important ethical principles and regulations in psychiatric research, this annotated volume offers extensive references and appendixes that aid in further understanding.
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Harold Alan Pincus, M.D., is Professor and Executive Vice Chairman of the Department of Psychiatry in the Western Psychiatric Institute and Clinic at the University of Pittsburgh School of Medicine, and Senior Scientist and Director of RAND at the University of Pittsburgh Health Research Institute in Pittsburgh, Pennsylvania. Jeffrey A. Lieberman, M.D., is Professor of Psychiatry, Pharmacology, and Radiology, Vice Chair of Research, and Director of Mental Health, Clinical Research Center, Department of Pychiatry at the University of North Carolina Medical School in Chapel Hill, North Carolina. Sandy Ferris is Assistant Director of the Office of Research at the American Psychiatric Association in Washington, D.C.
Now there is a single resource that puts the many facets of a widely misunderstood disorder in perspective. The American Psychiatric Publishing Textbook of Schizophrenia offers broad coverage that encompasses the current state of knowledge of its cause, nature, and treatment. Experts from North America and Europe address the complexity of schizophrenia in a comprehensive volume that leads readers from historical overview and epidemiology to consideration of comorbid conditions. It covers genetic and environmental causes, describes leading theories of schizophrenia, and explores the involvement of abnormal brain circuitry and the results of the latest neuroimaging studies.
As a guide to clinical practice, the book offers timely and informative guidelines for approaching cognitive impairment as a potential psychopharmacological target for treatment, strategies for improving functioning in individuals with social or vocational impairment, an overview of antipsychotic drugs, and a review of proven psychosocial interventions. Clinicians will also find keys to early identification of individuals vulnerable to psychoses, therapeutic approaches for first episodes, and special considerations for treatment of chronic schizophrenia. Squarely confronting this baffling disease, this textbook will serve as a dependable source of knowledge for students, scientists, and clinicians alike.
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