Synopsis
The p53 tumor suppressor gene the guardian of the genome protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of transcription factors (p53, p63, and p73) that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy.
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The p53 Family (Perspectives in Biology)
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p53 Family : A Subject Collection from Cold Spring Harbor Perspectives in Biology
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p53 Family : A Subject Collection from Cold Spring Harbor Perspectives in Biology
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The P53 Family
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The p53 Family: A Subject Collection from Cold Spring Harbor Perspectives in Biology
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p53 Family : A Subject Collection from Cold Spring Harbor Perspectives in Biology
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p53 Family : A Subject Collection from Cold Spring Harbor Perspectives in Biology
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Levine, A: P53 Family
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Condition: New. KlappentextThis volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their evolution, the regulatory mechanisms that control p53 activity, and . Seller Inventory # 595123088
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The P53 Family
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The P53 Family : A Subject Collection from Cold Spring Harbor Perspectives in Biology
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Buch. Condition: Neu. Neuware - This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their evolution, the regulatory mechanisms that control p53 activity, and the part played by p53 mutations in tumorigenesis. Seller Inventory # 9780879698300