The TGF-beta Family (Cold Spring Harbor Monograph) (Cold Spring Harbor Monograph Series): v. 50 - Hardcover

Rik Derynck; Kohei Miyazono

 
9780879697525: The TGF-beta Family (Cold Spring Harbor Monograph) (Cold Spring Harbor Monograph Series): v. 50

Synopsis

TGF-Beta is the prototype of a protein superfamily which, in humans, contain Mullerian inhibiting substance. This monograph draws on the world' s leading laboratories to comprehensively cover all aspects of the biology of TGF-Beta and serve as a reference work for both specialists and researchers less familiar with the field. Contents: Preface; Foreword (M.B. Sporn); 1. The Discovery of TGF-Beta: A Historical Perspective (H.L. Moses and A.B. Roberts); 2. TGF-Beta and the TGF-Beta Family (R. Derynck and M. Miyazono); CELL BIOLOGY: 3. TGF-Beta: A Multipotential Cytokine (S.H. Schilling, A.B. Hjelmeland, J.N. Rich, and X.-F. Wang); 4. Activins and Inhibins (E. Wiater and W. Vale); 5. The Bone Morphogenetic Proteins (T. Katagiri, T. Suda, and K. Miyazono);

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Review

The breadth and depth of the coverage of current TGF- b2; research is the most compelling feature of this book...[I]t is my recommendation that every principal investigator studying TGF- b2; should have a copy of this book...[T]he process of 'getting up to speed' becomes far less arduous. Development The book includes numerous figures and tables, which make each chapter accessible and pleasant to read. This volume will be of interest both for basic scientists concerned with topics such as transcriptional control of TFG- b2; signaling, as well as for translational scientists and clinicians focused on agents used to target the TGF- b2; signaling pathway...In summary, this book can be considered as a true TGF- b2; family encyclopedia. The Quarterly Review of Biology I found The TGF- b2; Family a great book. Tables and illustrations will surely prove useful in guiding the reader through complex problems and the book can be certainly recommended for teaching purposes. The clarity and comprehensiveness of the monograph, the eminence of the editors and authors, and the extensive bibliography at the end of each chapter make this book a 'must-have' reference for established investigators and clinicians and for newcomers attracted to TGF- b2; from various fields. Nature Cell Biology

Synopsis

The human transforming growth factor-beta (TGF-beta) family has at least 35 members. This monograph comprehensively covers various aspects of the biology of the family, and serves as a reference work for both specialists and researchers less familiar with the field.

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