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As more species' genomes are sequenced, computational analysis of these data has become increasingly important. The second, entirely updated edition of this widely praised textbook provides a comprehensive and critical examination of the computational methods needed for analyzing DNA, RNA, and protein data, as well as genomes. The book has been rewritten to make it more accessible to a wider audience, including advanced undergraduate and graduate students. New features include chapter guides and explanatory information panels and glossary terms. New chapters in this second edition cover statistical analysis of sequence alignments, computer programming for bioinformatics, and data management and mining. Practically oriented problems at the ends of chapters enhance the value of the book as a teaching resource. The book also serves as an essential reference for professionals in molecular biology, pharmaceutical, and genome laboratories.
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In conclusion, the second edition of 'Bioinformatics: Sequence and Genome Analysis' is an excellent textbook for bioinformatics introductory courses for both life sciences and computer science students, and a good reference for current problems in the field and the tools and methods employed in their solution. Briefings in Bioinformatics This second edition is a qualified success. Every chapter in the second edition appears to be rewritten extensively, and three useful new chapters have been added. As a result, the new edition tops out at 692 pages, and many of the problems with the first edition have been rectified... Overall, this second edition is a considerable improvement over the first and will be popular on the desks of many scientists as well as many students...If you find that you need a reference that covers the entire breadth of bioinformatics, you need to buy this book. Clinical ChemistrySynopsis:
The application of computational methods to DNA and protein science is an exciting development in biology. "Bioinformatics: Sequence and Genome Analysis" is a comprehensive introduction to this emerging field of study. The book has many valuable features. It is written for biologists who want to understand methods of sequence and structure analysis and how the necessary computer programs work. Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and illustrated. Underlying algorithms and assumptions are also explained for the non-specialist, and examples are presented in simple numerical terms rather than complex formulas and notation. Theoretical underpinnings are linked to biological problems and their solutions, while extensive tables provide descriptions and Web sources for a broad range of publicly available software. Based on the author's experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is an educational book, useful as a laboratory reference for investigators and also as a teaching reference for graduate and undergraduate students.
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Book Description Cold Spring Harbor Laboratory, 2001. Hardcover. Condition: New. Never used!. Seller Inventory # P110879695978