From Neuron to Brain: Cellular Approach to the Function of the Nervous System - Softcover

Kuffler, Stephen W.; Nicholls, John G.; Martin, A.Robert; Wallace, Bruce G.

Softcover

ISBN 10: 087893586X ISBN 13: 9780878935864

Publisher: Sinauer Associates Inc.,U.S., 1992

Synopsis

Up-to-date third edition which presents a coherant description of the nervous system from the perspective of modern work on molecular biology, cellular and developmental biology, biophysics, neurophysiology, neurochemistry and neuroanatomy. The scope of the book has been broadened with entirely new chapters on the biophysics and molecular biology of membrane channels, indirect mechanisms of synaptic transmission, the cellular and molecular biology of synaptic transmission, nervous system development, sensory receptors and systems, and motor systems. To accommodate this new information other subjects have been abbreviated or ammalgamated. Permeating the book are new concepts derived from experiments at the molecular level. Techniques such as patch clamping, gene cloning and expression, the use of monoclonal antibodies, and site-directed mutagenesis not only deepen but often simplify the presentation of topics related to signaling, synapse transmission, plasticity and development.

About this title

From the Publisher

Contents
PART I. INTRODUCTION

Principles of Signaling and Organization

PART II. SIGNALING IN THE NERVOUS SYSTEM

Ion Channels and Signaling

Structure of Ion Channels

Transport across Cell Membranes

Ionic Basis of the Resting Potential

Ionic Basis of the Action Potential

Neurons as Conductors of Electricity

Properties and Functions of Neuroglial Cells

Principles of Direct Synaptic Transmission

Indirect Mechanisms of Synaptic Transmission

Transmitter Release

Synaptic Plasticity

Cellular and Molecular Biochemistry of Synaptic Transmission

Neurotransmitters in the Central Nervous System

PART III. INTEGRATIVE MECHANISMS

Cellular Mechanisms of Integration and Behavior in Leeches, Ants, and Bees

Autonomic Nervous System

Transduction of Mechanical and Chemical Stimuli

Processing of Somatosensory and Auditory Signals

Transduction and Signaling in the Retina

Analysis of Form in Primary Visual Cortex

Functional Architecture of the Visual Cortex

Cellular Mechanisms of Motor Control

PART IV. DEVELOPMENT OF THE NERVOUS SYSTEM

Development of the Nervous System

Denervation and Regeneration of Synaptic Connections

Critical Periods in Visual and Auditory Systems

PART V. CONCLUSION

Open Questions

About the Author

JOHN G. NICHOLLS, SISSA, Trieste, Italy.

PAUL A. FUCHS, John Hopkins University School of Medicine.

A. ROBERT MARTIN, University of Colorado School of Medicine.

BRUCE G. WALLACE, University of Colorado School of Medicine.

Edition details

• Publisher: Sinauer Associates Inc.,U.S.
• Publication date: 1992
• ISBN 10: 087893586X
• ISBN 13: 9780878935864
• Binding: Paperback
• Language: English
• Edition number: 3
• Number of pages: 808