This work gives a presentation of theory and observation for students at the undergraduate and graduate level. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level. Integrated throughout the book are descriptions of molecular and other methods used to study natural populations as well as theory using actual data. Applications of the principles discussed are illustrated by worked examples.
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It is a pleasure to read this new edition of a classical textbook on population genetics. It shows very convincingly how population genetics has been revamped in the past twenty years by the introduction of new statistical and computational methods (in particular, coalescent theory), and the advent of genomic data, as well as how these developments changed a formerly rather arcane science and moved it toward the center of modern biology. In summary, the essence of population genetics is nicely condensed in this book. The presentation is wonderfully balanced between theory and observation, as well as classical and recent data sets and analysis tools. (Wolfgang Stephan, The Quarterly Review of Biology)
Contents:
(in brief)
Genetic and Statistical Background
Genetic and Phenotypic Variation
Organization of Genetic Variation
Population Substructure
Sources of Variation
Darwinian Selection
Random Genetic Drift
Molecular Population Genetics
Quantitative Genetics
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