Medicinal Chemistry: Principles and Practice - Softcover

 
9780854046317: Medicinal Chemistry: Principles and Practice

Synopsis

This book introduces the principles and practices of modern medicinal chemistry and covers all aspects of drug discovery from the initial lead to final development. It teaches how to convert a lead compound into a potential drug and provides recent case histories as examples of successes. Medicinal Chemistry is unique in dealing with the subject in such a practical way and is the only book currently available to bring together all areas of the subject in one volume. This breadth of coverage is supplemented by references to specialist monographs and reviews, where the reader can find more detail on specific topics of interest if required. Medicinal Chemistry is essential reading for students studying medicinal chemistry, as it provides a grounding in all the required disciplines and subjects. It will also be of great interest to chemists, biochemists and pharmacologists either already working in or contemplating a career in the pharmaceutical and allied industries.

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Review

"Overall an excellent book for those making a move into pharmaceutical/medicinal chemistry research and for those who wish to broaden their knowledge of all the disciplines involved in this area."

Synopsis

Covering key topics for drug discovery from the perspective of the practising industrial scientist and manager, this text presents all aspects of the subject of medicinal chemistry from initial lead through to final development. This edition builds on the successful foundations laid by the first edition by introducing new topics such as combinatorial chemistry, genomics and cheminformatics, alongside revised and updated original chapters. Introducing the cross-disciplinary topics needed, it embraces descriptions of targets, biology, metabolism and pharmacokinetics, genetics, patents and development chemistry. New case histories, strategy and tactics for drug discovery are also introduced. With many chapters written by practitioners from within the pharmaceutical industry, the text serves as a useful introduction to medicinal chemistry for new graduates and PhDs. It also serves to update more experienced scientists on the newer technologies in the field.

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