Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals. Topics covered include structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, evolution of DNA sequences, comparative chromosome mapping and painting, genome databases, gene prediction and the use of genomic information to understand inherited diseases. Contributors include leading researchers from Europe, USA, Australia and Japan.
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Since graduation from Novosibirsk State University (Russia) in 1969 A. Ruvinsky has been working in several fields of genetics for more than 40 years. He received his PhD in 1974 and Dr.Sc. in 1985. In 1986 A. Ruvinsky was elected as head of laboratory of animal genetics and 1988 as Vice Director of the Institute of Cytology and Genetics of Russian Academy of Sciences. In 1993 A. Ruvinsky joined the University of New England, Australia. Professor Ruvinsky published more than 100 refereed papers in leading genetic journals and edited 14 books so far. This includes the series of books on mammalian genetics, which currently undergoes 2nd edition. His conceptual book "Genetics and Randomness" was published in 2009.
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