Methods for NEURAL ENSEMBLE RECORDINGS (Frontiers in Neuroscience) - Hardcover

Hardcover

ISBN 10: 0849333512 ISBN 13: 9780849333514

Publisher: CRC Press, 1998

Synopsis

Neuroscientists have long recognized the importance of understanding the underlying principles of information processing by large populations of neurons. Methods for Neural Ensemble Recordings explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. Since current methods allow one to simultaneously record the extracellular activity of up to 100-150 neurons for days or even weeks, neural ensemble recordings have been used to address long-standing issues in development, learning, memory, sensorimotor integration, sensory information processing, and neuronal plasticity.

EXAMINES THE MANY POSSIBLE APPLICATIONS FOR THIS REVOLUTIONARY METHOD

Each chapter offers a step-by-step description for the implementation of a particular technique or experimental paradigm employing simultaneous multiple electrode recordings. The techniques described can be used in applications that impact a large group of life scientists, including:

drug screening (pharmacology) in both in vitro and in vivo preparations

developmental studies and studies of neuronal plasticity

chronic monitoring of neuronal function in behavioral studies

physiological monitoring of neuronal activity in cell cultures and brain slices

physiological monitoring of neuronal activity in neurons trafected with genetic vectors

chronic monitoring of physiological changes in populations of neurons during learning of new sensorimotor and cognitive tasks

About this title

Review

"This volume leads readers through microelectrode design, choice and availability; hardware and software for simultaneous sampling; and neural ensemble data analysis." -Joel L. Davis, Cognitive & Neural Systems Division, Office of Naval Research, Arlington, Virginia, USA "Nicolelis' long chapter is the most informative. It provides a clear soup-to-nuts recipe for recording from neuronal ensembles." -Joel L. Davis, Cognitive & Neural Systems Division, Office of Naval Research, Arlington, Virginia, USA

Edition details

• Publisher: CRC Press
• Publication date: 1998
• Language: English
• ISBN 10: 0849333512
• ISBN 13: 9780849333514
• Binding: Hardcover
• Edition number: 1
• Number of pages: 272
• Editor: Nicolelis Miguel A. L.