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Synopsis
"Modern Cell Biology, Volume 6" is comprised of four reports that explore the latest advances in different areas of cellular research. In the first study, the control of gene expression by testosterone in murine renal cells is explored. Complementary DNA probes are used to examine their structure and expression under various conditions of hormone treatment, as well as in different genetic backgrounds. The structure, pool fluctuations, metabolism, and biological functions of adenosine-tetraphosphoadenosine (Ap4A) are covered in chapter two, including a review of a working hypothesis on the possibility of Ap4A as a link in the intracellular signal chain of cell proliferation. Chapter three focuses on the use of Uukuniemi virus - a member of the Bunyaviridae family of arthropod-borne viruses - as a model system to study the properties of Golgi specific proteins. Current knowledge on sulfation of proteins on tyrosine residues is summarized in the final chapter, with an emphasis on occurrence, cell biology, enzymology, functional aspects, and future perspectives for study.
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Modern Cell Biology
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