Items related to Methods for Studying Platelets and Megakaryocytes
Synopsis
Platelets have been linked to such critical conditions as unstable angina and smooth muscle cell proliferation. To control their damaging impact, pharmacologists are attempting to develop antiplatelet drugs through intense research upon platelets and megakaryocytes. This contributed volume provides a timely account of the methods and techniques that are being used in this important research. Contains a comprehensive review of the methods used to study intracellular regulators such as products of phospholipid and arachidonate metabolism, intracellular calcium, and cAMP. Covers in detail methods for studying important platelet proteins such as receptors, cytoskeletal elements, contractile components, and coagulant proteins. Also discusses a variety of techniques such as high-pressure liquid chromatography, monoclonal antibodies, affinity labelling ELISA, radioimmunoassays, and the more classical biochemical and pharmacologic approaches.
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