Vanadium is now known to be one of the more biologically important transition elements. This volume focuses on vanadium chemistry and biochemistry and summarizes the role of vanadium in treating diabetes, concluding with a discussion of a human trial study. The volume looks in particular at model compounds that mimic the chemistry of nitrogenases as haloperoxidases. It also uncovers evolutionary aspects of haloperoxidases while examining structural and sequence relationships between these compounds and acid phosphatases. Aspects of the essentiality, toxicology, and pharmacology are discussed along with insulin-mimetic compounds and their influences in cell cultures.
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"The November 1997 symposium focused attention on the importance of understanding the interrelationships among the aqueous chemistry, the biochemistry, and the therapeutic utilization of vanadium compounds. The 28 contributions in this proceedings volume are divided into the three areas. Examples of the topics are insulin- mimetic action of selected vanadium compounds, synthetic models for vanadium haloperoxidases, the vanadium-containing nitrogenase system of Azotobacter vinelandii, a possible role for amavadine in some Amanita fungi, and vanadium salts in the treatment of human diabetes mellitus."--SciTech Book News
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