This is the first book of its kind to bring together the seemingly diverse fields of medicinal chemistry, agrochemicals, and chemical toxicology with an examination of their common mechanistic ground. This volume explores how a variety of statistical and computer modeling techniques can be used to design biologically active mechanisms, elucidate the pertinent structure-activity relationships, and define the characteristics of receptor and receptor-ligand interactions. An introductory section focuses on historical perspectives, with subsequent chapters providing broad coverage of agrochemical mechanisms, drug mechanisms, and toxicity mechanisms.
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Developed from a symposium held in Los Angeles, CA, September 1988. The contributions explore how a variety of statistical and computer modeling techniques can be used to design biologically active mechanisms, elucidate the pertinent structure-activity relationships, and define the characteristics of receptor and receptor-ligand interactions. An in
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