This work integrates the environmental triggers of multiple sclerosis (MS) with genetic susceptibility to the disease, and presents developments in MS investigation. It highlights epidemiology, aetiology, pathogenesis, pathology, clinical features, and therapy. The book explains the most efficacious treatment strategies, including beta interferons, copolymer 1, cladribine, imuran, methotrexate, corticosteroids, and IV gamma globulin as well as symptomatic therapies such as symmetrel, cylert, tegretol, dilantin, lioresol, antidepressants and ditropan
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"International praise for the previous editions... This is a substantial multi-authored text covering all the important aspects of current knowledge on multiple sclerosis.... ...well produced, illustrated and abounds with well-chosen references... "-Journal of Neurology, Neurosurgery and Psychiatry ...a well-written book that describes both classic and recent knowledge about multiple sclerosis. The contributors are outstanding.... ...clearly and comprehensively organized. -Canadian Medical Association Journal ...a Baedeker of multiple sclerosis research, and a guide to the basic neurobiology of the disorder.... ...excellent sections of undeniable general appeal and great practical use. -Annals of Internal Medicine ...most useful to residents and fellows in neurology...to neurologic clinicians, who are interested in comprehensive and current advances...and to both basic and clinical investigators. -Mayo Clinic Proceedings ...helps to understand the links between the actual knowledge...and the therapies that are applicable in patients....This book is useful for neurologists who have a special interest in multiple sclerosis and look for an overview as well as for the rationale for using newly developed therapies. -European Neurology "present[s] the latest information concerning the immunopathology of this disease and new treatment modalities for those cursed with this affliction. highly recommended for all academic health science library collections. "-E-Streams
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