Items related to Protease Inhibitors in AIDS Therapy (Infectious Disease...

Protease Inhibitors in AIDS Therapy (Infectious Disease and Therapy) - Hardcover

Ogden, Richard C.; Flexner, Charles

 
9780824704612: Protease Inhibitors in AIDS Therapy (Infectious Disease and Therapy)
Hardcover
ISBN 10: 0824704614 ISBN 13: 9780824704612
Publisher: CRC Press, 2001

Synopsis

Details the evolution of HIV protease inhibitors from molecular development through medical applications!

Considering the latest class of revolutionary drugs fighting against HIV infection and AIDS, this comprehensive reference thoroughly examines the development and properties of HIV protease inhibitors from clinical and scientific perspectives, discussing how protease inhibitors changed the FDA approval process-enhancing the collaboration between regulatory authorities and drug developers.

Spotlights protease inhibitors as the cornerstone drugs of the first HAART regimens-key components of long-term viral suppression and immune restoration, and in secondary and tertiary regimens!

Evaluating protease inhibitors as therapeutic options and research tools, Protease Inhibitors in AIDS Therapy

  • reviews the impact of advances in recombinant DNA technology for understanding and treating HIV and AIDS
  • highlights a variety of strategies and techniques for drug discovery and development illustrated by success stories of pharmaceutical companies and biotechnology start-up firms
  • summarizes the pharmacokinetics, metabolism, and drug interactions of protease inhibitors
  • details preliminary clinical studies on oral bioavailability, pharmacokinetic profiling, efficacy, resistance, and tolerability
  • describes available efficacy data for marketed inhibitors and those in clinical development
  • reports on efforts to manage antiviral resistance in the clinic and improve patient adherence to complex drug therapy
  • and more!
    Containing more than 600 helpful literature references, drawings, photographs, and tables, Protease Inhibitors in AIDS Therapy serves for an essential reference for infectious disease specialists, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, hematologists, hepatologists, and medical students in these disciplines.

    • "synopsis" may belong to another edition of this title.

    Publisher
    CRC Press
    Publication date
    2001
    Language
    English
    ISBN 10 
    0824704614
    ISBN 13 
    9780824704612
    Binding
    Hardcover
    Edition number
    1
    Number of pages
    328