This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated.1919 Excerpt: ... CHAPTER V THE PHYSIOLOGY OF FERTILIZATION I. INTRODUCTION It is commonly said that there are two main problems in the physiology of fertilization, viz.: the initiation of development, or activation, and biparental inheritance; but these are more properly results of fertilization. Indeed so long as we regard fertilization primarily as a function of prospective significance in the life of the organism we shall miss the more specific aspects of the process. Once fertilization is accomplished development and inheritance may be left to look after themselves. Fertilization must be regarded as a reaction possessing very definite biological and biochemical characters. But it is not a single reaction in either a biological or chemical sense; it is rather a series of reactions which cannot be regarded as complete until full capacity for development and inheritance is attained by the zygote. Fertilization may therefore be partial, which may be indicated by early cessation of the developmental process or deficiency of developmental energy. It is obvious that partial fertilization will furnish an important means of analysis. The reactions of fertilization form an irreversible series, though it is conceivable that some of them taken singly may be reversible. Spermatozoa have no effect on already fertilized eggs and do not penetrate into them; this condition arises very early in the fertilization reactions, so that the entrance of more than one spermatozoon does not usually occur. With reference to reversibility the ovum differs from most cells. A nerve cell or a gland cell or a muscle cell after functioning returns to the functional condition again; but, so far as our evidence goes, this is not true of the egg cell or of the spermatozoon; their functioning is essentially...
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