Gene Expression: General and Cell-Type-Specific (Progress in Gene Expression) - Hardcover

Hardcover

ISBN 10: 0817636056 ISBN 13: 9780817636050

Publisher: Birkhauser Boston Inc, 1993

Synopsis

This book is the first volume in a new series Progress in Gene Expres- sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa- tion. As we see huge efforts mounting all over the developed world to understand the structure and organization of several complex eukaryotic genomes in the form of Gene Projects and Genome Centers, we have to remember that without understanding the basic mechanisms that gov- ern the use of genetic information, much of this effort will not be very productive. Fortunately, however, research during the past seven years on the mechanisms that control gene expression in eukaryotes has been extremely successful in generating a wealth of information on the basic strategies of transcriptional control. (Although regulation of gene ex- pression is exerted at many different levels, much of the emphasis in this series will be on transcriptional control. A future volume, however, will deal with other levels of regulation). The progress in understanding the control of eukaryotic transcription can only be appreciated by realizing that seven years ago we did not know the primary structure of a single sequence specific transcriptional activator, and those whose primary structures were available (e. g. , homeo- domain proteins) were not yet recognized to function in this capacity.

About this title

Synopsis

This exciting collection of review articles provides a comprehensive introduction to this important area of molecular biology - written by the world's top molecular and cellular biologists. Each chapter begins with the basic concepts and progresses to a state-of-the-art review of current literature, making the book invaluable for students entering the field. Seasoned researchers will value the keen insights into related areas, such as immunology, neuroscience, and endocrinology. Topics include: Basic transcription; Cell differentiation and plasticity; Gene regulation by steroid hormones; Cellular proliferation; Muscle-specific gene expression; Gene expression and differentiation in the hematopoietic system; Hepatic gene expression and its regulation; Gene expression and differentiation of neuroendocrine cells. This book is the first in a series covering all aspects of gene expression and regulation, and related areas of molecular biology. It is essential reading for all molecular biologists, cell biologists, biochemists, and biotechnologists.

Edition details

• Publisher: Birkhauser Boston Inc
• Publication date: 1993
• Language: English
• ISBN 10: 0817636056
• ISBN 13: 9780817636050
• Binding: Hardcover
• Number of pages: 304
• Editor: Karin M.