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Synopsis
This practical guide for both clinical and research geneticists explains how to calculate an individual's genetic risk based on information available from genetic testing and family pedigrees. The book begins with the general theory of estimating genetic risks, then progresses through familial and isolated cases, both simple and complex. Worked examples are provided throughout the text. The disorders are selected to be as widely applicable or adaptable as needed. New to this edition are sections on consanguinity, multipoint linkage analysis, non-parametric methods, homozygosity mapping and physical mapping. There is also a new chapter on other DNA-based calculations, including sections on paternity, zygosity, family reconstructions and quantification aof mitochondrial mutations.
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About the Author
Peter J. Bridge is director of the Molecular Diagnostic Laboratory at Alberta Children's Hospital in Calgary, Alberta, Canada.
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The Calculation of Genetic Risks : Worked Examples in DNA Diagnostics
Published by
Johns Hopkins University Press, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
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The Calculation of Genetic Risks: Worked Examples in DNA Diagnostics
Published by
The Johns Hopkins University Press, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
Used
Hardcover
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Condition: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Seller Inventory # Z1-I-032-02442
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The Calculation Of Genetic Risks: Worked Examples In Dna Diagnostics
Published by
Johns Hopkins Univ Press, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
Used
Hardcover
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Hardcover. Condition: Very Good. Dust Jacket Condition: No Dustjacket. Later Edition. ISBN 9780801857447. Hardback. Second edition. No dustjacket; bound in gray boards with gold gilt lettering on black field. Very slight wear to corners and edges; otherwise tight, sound and unmarked in Very Good to Near Fine condition. No Signature. Seller Inventory # 4218891
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The Calculation of Genetic Risks: Worked Examples in DNA Diagnostics
Published by
The Johns Hopkins University Pre, 1997
ISBN 10: 0801857449
ISBN 13: 9780801857447
Used
Hardcover
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