The Hematopoietic Microenvironment: The Functional and Structural Basis of Blood Cell Development (The Johns Hopkins Series in Hematology/Oncology) - Hardcover

Long

Hardcover

ISBN 10: 0801845661 ISBN 13: 9780801845666

Publisher: John Hopkins University Press, 1993

Synopsis

Sophisticated cloning techniques now make it possible for investigators to study the production and development of blood at both the cellular and the molecular levels. In "The Hematopoietic Microenvironment", Michael Long and Max Wicha bring together a group of contributors to offer a state-of-the-art overview of the cellular and molecular basis of blood cell development. Topics examined in the book include cell types capable of elaborating hematopoietic growth factors, their regulation of both growth factor production and matrix deposition, and interactions of growth factors and haematopoietic progenitor cells with components of the extracellular matrix. Consideration is also given to the clinical implication of disorders of the haematopoietic microenvironment. Previously available largely in widely scattered journal articles and other difficult-to-reach sources, the up-to-date information in this book represents an important contribution to a field of growing importance. It should be of particular interest to professionals in haematology and oncology, as well as in molecular biology and genetics.

About this title

Review

"A comprehensive and timely introduction to microenvironmental issues... The very incompleteness of the picture it paints will no doubt provide a challenge to medical students entering the field." -- British Journal of Haematology

Edition details

• Publisher: John Hopkins University Press
• Publication date: 1993
• Language: English
• ISBN 10: 0801845661
• ISBN 13: 9780801845666
• Binding: Hardcover
• Number of pages: 336