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Synopsis
This volume brings together the work of leading medical chemists and represents efforts on the part of drug designers to produce small molecules aimed at preventing or treating brain-related diseases. Prominent among these are contributions on agents of value in Alzheimer's therapy; anxioselective anxiolytics; novel antipsychotics and the activation of dopamine autoreceptors; the role of the neurotransmitter dopamine in cocaine addiction; multiple populations of serotonin receptors; designing specific 5-HT3 receptor antagonists; glutamatergic receptor modulation; developing compounds capable of interacting with second messenger systems; and brain targeting of biologically active compounds. Also featured are examples of computer-assisted molecular modelling (CAMM) described throughout the text.
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Drug Design for Neuroscience
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Raven Press, New York, 1993
ISBN 10: 0781700612
ISBN 13: 9780781700610
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Drug Design for Neuroscience
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