Channelopathies of the Nervous System - Hardcover

Hardcover

ISBN 10: 0750645075 ISBN 13: 9780750645072

Publisher: Butterworth-Heinemann, 2001

Synopsis

Neurologists and other neuroscientists, Pharmacologists, physiologists, geneticists and molecular biologists will find this book both a good read and a valuable reference tool.

* A timely and unique reference focusing on the rapidly developing field of channelopathies of the nervous system from brain to muscle
* Written specifically for the clinical neurologist and neuroscientist
* Reviews the scientific principles of ion channel function and the clinical manifestations of the ion channel dysfunction

About this title

From the Publisher

It then focuses on the clinical manifestations of ion channel dysfunction. Beginning with basic physiology, molecular biology, genetics and pharmacology of the ion channels, it next considers methods of assessing ion channel function in vitro and in clinical practice. It elucidates the role of altered ion channel gene expression in normal development, and in response to injury or demyelination. It reviews the neurological diseases caused by both hereditary or acquired channelopathies.The chapters are written by international authorities and brings together a unique combination of the scientific and clinical for clinical neurologists and other neuroscientists. The chapters provide information not readily available in current textbooks: common neurological disorders such as pain syndromes, epilepsy, and migraine as well as rarer ion channel diseases like paroxysmal dyskinesias, episodic ataxias, hyperrekplexia and muscle disorders. 7

A timely and unique reference focusing on the rapidly developing field of channelopathies of the nervous system from brain to muscle

7

Written specifically for the clinical neurologist and neuroscientist

7

Reviews the scientific principles of ion channel function and the clinic Weight al manifestations of ion channel dysfunctionNeurologists and other neuroscientists, pharmacologists, physiologistTOC: Foreword Introduction Physiology of ion channels Molecular biology of ion channels Pharmacology of ion channels Techniques for assessing ion channel function in vitro Techniques for assessing ion channel function in vivo Plasticity of channels Role of channels in pain syndromes Role of channels in demyelination Myotonias Periodic paralysis Hyperkalaemic and Hypokalaemic Malignant hyperthermia Congenital m yasthenia Rejection of outliers Myasthenia gravis and Lambert Eaton myasthenia Neuromyotonia Periodic ataxias and SC6 etc Epilepsies Paroxysmal dyskinesias Hyperreplexia Migraine Ciguatera and other channel toxins Myotonias MyoDys, PROMM, Schwartz Jampel Anderson's syndrome Conclusion

Synopsis

Neurologists and other neuroscientists, pharmacologists, physiologists, geneticists, and molecular biologists will find this book both a good read and a valuable reference tool.

Edition details

• Publisher: Butterworth-Heinemann
• Publication date: 2001
• Language: English
• ISBN 10: 0750645075
• ISBN 13: 9780750645072
• Binding: Hardcover
• Number of pages: 347
• Editor: Rose BSc MD FRCP Michael R., Griggs MD FACP FAAN Robert C.