Bioactive Compounds from Natural Sources: Isolation, Characterization and Biological Properties - Hardcover

Hardcover

ISBN 10: 0748408908 ISBN 13: 9780748408900

Publisher: CRC Press, 2000

Synopsis

Interest in obtaining biologically active compounds from natural sources has recently spiked due to their low toxicity, complete biodegradability, availability from renewable sources, and in most cases, low cost. Taking an interdisciplinary approach, Bioactive Compounds from Natural Sources: Isolation, Characterization, and Biological Properties covers general methods and main topics in the research field of bioactive natural products. The book describes general screening methods, modern HPLC hyphenated techniques, and NMR methods in the structural elucidation of compounds and devotes individual chapters to specific topics of research. Surveys on compounds displaying important pharmacological activities are presented in chapters devoted to Mexican medicinal plants, anti-tumor drugs of natural origin, cancer chemopreventive flavonoids, and metabolites displaying anti-HIV, antioxidative, antimalarial, and anti-inflammatory activity. The final chapters are devoted to representative examples of research into marine metabolites: immunomodulating marine glycolipids and surveys of bioactive compounds from marine opisthobranchs and Japanese soft corals. With its focus on modern approaches to the isolation of biologically active natural products, this book encourages interdisciplinary work among chemists, pharmacologists, biologists, botanists, and agronomists with an interest in bioactive natural products.

About this title

Review

Praise for the Previous Edition

"...The title of the book gives a good description of the chapters, which are very detailed and interesting in their multi-disciplinary content of biology, biochemistry and chemistry. Since Professor Tringali is the editor, it is not surprising that the chapters tend to include useful details of NMR data. All of the chapters have a good literature reference list. This book is recommended to all natural products researchers."
―Robert J. Nash, Institute of Grassland and Environmental Research, in Phytochemistry

"The book is well indexed with a detailed subject index and a separate natural source index listing the genus and species of each sample described in the text. References are through 1998, and in general the book is well organized with the format being consistent throughout the volume, making it easy to read. This book is certain to be of interest to those individuals new to the field of natural products as well as to senior scientists interested in a review of the subject areas covered by chapter."
―Mark T. Hamann, The University of Mississippi, in Journal of Natural Products Review

"... All in all, the book, including the excellent references, provides a good introduction to the methods and classes of natural products. It is an excellent starting point for new graduate students, and a useful reference for practitioners in the natural products field."
―W. Ayer, University of Alberta, Royal Society of Chemistry

Synopsis

In recent years, a renewed interest in obtaining biologically active compounds from natural sources has been observed. Contributing to this world-wide attention towards formulations based on natural products are their low or absent toxicity, their complete biodegradability, their availability from renewable sources, and, in most cases, their low-cost if compared with those of compounds obtained by total chemical synthesis. A further drive to the study of compounds obtainable from natural sources is the increasing consciousness that destruction or severe degradation of rain forests and other wild habitats, including seas and oceans, will unavoidably result in the loss of unexamined species and consequently of potentially useful compounds. Owing to this renewed attention to pharmaceuticals, agrochemicals and nutraceuticals (functional foods) obtained from natural sources, the study of bioactive secondary metabolites, traditionally carried out mainly by chemists, has increasingly attracted the attention of pharmacologists, biologists, botanists, agronomists, etc. stimulating co-operative work.

This book reinforces the interdisciplinary approach to the study of bioactive natural products, suggesting new research projects to scientists already involved with bioactive natural products and possibly attracting further researchers to this field. The book includes chapters focused on general methods; main topics in the research field of bioactive natural products; surveys on natural compounds displaying important pharmacological activities; and marine metabolites. This work offers an overview of the modern methodology in the search for bioactive compounds from natural sources, and will be useful to advanced students and research scientists from various disciplinary sectors related to natural products. Tringali; Corrado University of Catania, Italy,

Edition details

• Publisher: CRC Press
• Publication date: 2000
• Language: English
• ISBN 10: 0748408908
• ISBN 13: 9780748408900
• Binding: Hardcover
• Edition number: 1
• Number of pages: 704
• Editor: Tringali Corrado