DNA, Words and Models: Statistics of Exceptional Words - Hardcover

Robin, S.; Rodolphe, F.; Schbath, S.

Hardcover

ISBN 10: 052184729X ISBN 13: 9780521847292

Publisher: Cambridge University Press, 2005

Synopsis

This book introduces mathematical and statistical ideas used for pattern analysis in computational biology.

About this title

Review

'For statisticians with a little background in biology, this book delivers a very readable presentation on the analysis of DNA sequences to determine whether a motif is of statistical significance due to its overabundance (or under-abundance) in terms of frequencies or location. This book is concise but sufficiently detailed. Biologists without a background in mathematical statistics may find the learning curve a little steep but tractable. The authors' continuous use of practical examples will be greatly appreciate by biologists and statisticians alike. This book is one of a kind, and I recommend it to any statistician interested in learning about DNA sequences and motifs.' Journal of the American Statistical Association

Book Description

One of the most important problems in computational biology is whether a particular gene sequence (mathematically, a 'word') is simply random or is of biological significance, for example, because of its frequency or location. This book introduces the mathematical and statistical ideas used in solving this so-called exceptional word problem.

Edition details

• Publisher: Cambridge University Press
• Publication date: 2005
• Language: English
• ISBN 10: 052184729X
• ISBN 13: 9780521847292
• Binding: Hardcover
• Number of pages: 158