Computational Analysis of Biochemical Systems: A Practical Guide for Biochemists and Molecular Biologists - Softcover

Voit, Eberhard O.

Softcover

ISBN 10: 0521785790 ISBN 13: 9780521785792

Publisher: Cambridge University Press, 2000

Synopsis

Throughout the foreseeable future, research in medicine, molecular biology, and biotechnology will be dominated by scientific advances resulting from the Human Genome Project. Knowledge of genomes will elucidate disease patterns and promise improved and personalized treatments. Food and drug development will be revolutionized by focused manipulation of genes and biochemical processes. Researchers will begin to construct metabolic pathways from scratch. A true understanding of genetic and metabolic function and design will depend on mathematical and computational methods for analyzing biochemical systems. It will require new ways of thinking and novel approaches of integrative analysis. This book teaches biochemists and molecular biologists the use of modern computational methods for the analysis of complex biomedical systems without assuming more than a modest background in mathematics. The book begins with representations of biochemical systems, provides guidelines for setting up models, discusses in detail mathematical and computational methods of parameter estimation and model analysis, and ultimately connects to the modern literature with four detailed case studies. Every step is illustrated with examples and explored with accompanying software.

About this title

About the Author

Eberhard O. Voit is Professor of Biometry in the Department of Biometry and Epidemiology at the Medical University of South Carolina. PLAS was created by Antônio E. N. Ferreira, Instructor in the Department of Chemistry and Biochemistry at the University of Lisbon, Portugal.

Edition details

• Publisher: Cambridge University Press
• Publication date: 2000
• Language: English
• ISBN 10: 0521785790
• ISBN 13: 9780521785792
• Binding: Paperback
• Number of pages: 544