The Human Pain System: Experimental and Clinical Perspectives - Hardcover

Lenz, Frederick A.; Casey, Kenneth L.; Jones, Edward G.; Willis, William D.

Hardcover

ISBN 10: 0521114527 ISBN 13: 9780521114523

Publisher: Cambridge University Press, 2010

Synopsis

Pain is a subject of significant scientific and clinical interest. This has resulted both from realistic rodent models, and the publication of imaging, psychological and pharmacological studies in humans. Investigators studying rodents refer to anatomical and physiological studies in non-human primates to make their results relevant to humans. Psychophysical and pharmacological studies in humans are interpreted in terms of anatomical and physiological studies in animals; primarily evidence from rodents and cats. There are significant differences in pain mechanisms between these species and primates. Over 20 years of imaging studies have demonstrated the activation of human cortical and subcortical structures in response to painful stimuli. Interpretation of these results relies upon an understanding of the anatomy and physiology of these structures in primates. Jones, Lenz, Casey and Willis review the anatomy and physiology of nociception in monkeys and humans, and provide a firm basis for interpreting studies in humans.

About this title

Review

'... good quality paper and multiple images and figures ... inviting to read. ...would I recommend this book as a valuable addition to your book shelf? In my opinion this is a definite YES. definitely good value for money ... the knowledge in this book will not date quickly. It is a fundamental reference book that comprehensively covers knowledge about pain processing to date. It will act as the corner stone from which understanding of emerging evidence about the pain pathways can be developed as new literature is published.' Perception

Book Description

The development of rodent models and the publication of imaging, psychological and pharmacological studies in humans has put pain to the forefront of scientific and clinical research. The authors review the anatomy and physiology of nociception in monkeys and humans and provide a basis for interpreting these studies.

Edition details

• Publisher: Cambridge University Press
• Publication date: 2010
• ISBN 10: 0521114527
• ISBN 13: 9780521114523
• Binding: Hardcover
• Language: English
• Edition number: 1
• Number of pages: 648