Mass Spectrometry: Instrumentation, Interpretation, and Applications (Wiley Series on Mass Spectrometry) - Hardcover

Kraj, Agnieszka; Desiderio, Dominic M.; Nibbering, Nico M.

Hardcover

ISBN 10: 0471713953 ISBN 13: 9780471713951

Publisher: Wiley, 2009

Synopsis

With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.

About this title

About the Author

Rolf Ekman, PhD, is a Professor of Neurochemistry at University of Gothenburg in Sweden.

JERZY SILBERRING, PhD, is the Head of the Department of Neurobiochemistry in the Department of Chemistry and the former deputy head of the Regional Laboratory of Physicochemical Analyses at Jagiellonian University in Krakow, Poland.

Ann M. Westman-Brinkmalm, PhD, is a Junior Research Fellow at the Sahlgrenska Academy at University of Gothenburg in Sweden.

Agnieszka Kraj, PhD, is an Assistant Professor in the Department of Neurobiochemistry, Faculty of Chemistry at Jagiellonian University in Krakow, Poland.

From the Back Cover

Helps students fully leverage mass spectrometry in whichever field of research they choose

Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.

This text is divided into three parts that guide students from basic principles to applications:

• Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.

• Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.

• Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.

Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.

Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.

This text is divided into three parts that guide students from basic principles to applications:

• Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.

• Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.

• Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.

Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.

Edition details

• Publisher: Wiley
• Publication date: 2009
• Language: English
• ISBN 10: 0471713953
• ISBN 13: 9780471713951
• Binding: Hardcover
• Edition number: 1
• Number of pages: 400
• Editor: Ekman Rolf, Silberring Jerzy, Westman-Brinkmalm Ann M.