Biomedical Applications of Mass Spectrometry: v. 34 (Methods of Biochemical Analysis) - Softcover

Softcover

ISBN 10: 0471613037 ISBN 13: 9780471613039

Publisher: Wiley–Blackwell, 1991

Synopsis

The purpose of this book is to give the reader, both the novice and the authority, a presentation of the application of mass spectrometry to a variety of biological problems. It begins by giving an overview of mass spectrometry, including a review of some of the recent advances that make this field of analytical biochemistry so exciting. Each subsequent chapter is prepared by an authority in the field. The chapters are not a compilation of methods but, rather, they provide insight into approaches that mass spectroscopists have used to solve these problems. Each chapter provides guidance in using appropriate methods for isolation and purification of the compound class prior to analysis or characterization by mass spectrometry. It also provides a tutorial on mass spectral interpretation based on the fragmentation pathways usually encountered for the particular compound type. In many cases, chemical modification of the parent compound and corresponding mass shifts in the spectrum are co-ordinated through reaction schemes and didactic descriptions. Modern approaches to analysis based on fast-atom bombardment are described in conjunction with the more conventional analysis by electron impact and chemical- ionization mass spectrometry.

About this title

From the Back Cover

Biomedical Applications of Mass Spectrometry Edited by Clarence H. Suelter and J. Throck Watson
This unusual text is not simply a compilation of mass spectrometric methods but provides, instead, insight into specific approaches mass spectroscopists use when applying the technique to a variety of biological problems. Each chapter provides guidance in using the appropriate methods for isolating and purifying the compound class prior to mass spectrometric analysis. Covered in-depth are the mass spectrometry of carbohydrates, peptide sequencing by mass spectrometry, mass spectrometry of nucleic acid components, and mass spectrometry in pharmacology. This definitive look at a growing facet of the science is an essential reference for biochemists, biological chemists, bioanalytical chemists, and students. 1990 (0-471-61303-7) 396 pp.

Edition details

• Publisher: Wiley–Blackwell
• Publication date: 1991
• Language: English
• ISBN 10: 0471613037
• ISBN 13: 9780471613039
• Binding: Paperback
• Number of pages: 396
• Editor: Suelter Clarence H., Watson J. Throck