Handbook of Comparative Genomics: Principles and Methodology - Hardcover

Saccone, Cecilia; Pesole, Graziano

 
9780471391289: Handbook of Comparative Genomics: Principles and Methodology
Hardcover
ISBN 10: 047139128X ISBN 13: 9780471391289
Publisher: Wiley-Liss, 2003

Synopsis

This comprehensive reference covers the comparative methodology involved in studying molecular evolution. Providing a practical introduction to the role of bioinformatics in comparative genomics, this publication further discusses the basic technology used in genome sequencing projects and provides an overview of genome storage databases currently in use.
This timely and cutting-edge text also:
* Reviews the basic principles of genomics and gene
expression analysis
* Discusses analytic methods in proteomics and
transcriptomics
* Includes a comprehensive list of Web resource

"synopsis" may belong to another edition of this title.

About the Author

Cecilia Saccone is Professor of Molecular Biology at the University of Bari as well as the chair of the National Research Council (CNR) in Bari, Italy.
Graziano Pesole is a professor in the Department of Physiology and General Biochemistry at the University of Milan, Italy.

From the Back Cover

Handbook of Comparative Genomics: Principles and Methodology is a practical text for students and researchers covering basic and applied problems in the emerging field of comparative functional genomics. It offers a comparative perspective on the state of the art and key principles of genome sequencing, expression, evolution, and phylogenetics in organelles, prokaryotes, model organisms, and humans. Moreover, the Handbook provides a unique and thorough treatment of biological databases, analysis of the transcriptome and proteome, and the bioinformatic approaches for comparative genome analysis.

The text begins with an introduction to important features of completely sequenced genomes from mitochondria, C. elegans and Arabidopsis to Drosophila and humans. The next section covers cutting-edge analytic approaches involving ESTs, SAGE, DNA microarrays, protein biochips, and 2D gel electrophoresis. The following section deals comprehensively with computational approaches to comparative genome and proteome sequence analysis, including sequence assembly, pattern searching, gene and protein function prediction, and structure prediction. The text concludes with a section discussing genome evolution and molecular phylogenetics. This timely and cutting-edge text also:
* Presents both the concepts and methodology of comparative genomics
* Reviews the basic principles of genomics and gene expression analysis
* Covers the bioinformatics approaches to comparative analysis
* Discusses analytic methods in proteomics and transcriptomics
* Includes a comprehensive list of Web resources

The authors draw upon their wealth of teaching and research experience to offer a coherent presentation appropriate for students, trainees, researchers, and scientists across the life sciences.

From the Inside Flap

Handbook of Comparative Genomics: Principles and Methodology is a practical text for students and researchers covering basic and applied problems in the emerging field of comparative functional genomics. It offers a comparative perspective on the state of the art and key principles of genome sequencing, expression, evolution, and phylogenetics in organelles, prokaryotes, model organisms, and humans. Moreover, the Handbook provides a unique and thorough treatment of biological databases, analysis of the transcriptome and proteome, and the bioinformatic approaches for comparative genome analysis.

The text begins with an introduction to important features of completely sequenced genomes from mitochondria, C. elegans and Arabidopsis to Drosophila and humans. The next section covers cutting-edge analytic approaches involving ESTs, SAGE, DNA microarrays, protein biochips, and 2D gel electrophoresis. The following section deals comprehensively with computational approaches to comparative genome and proteome sequence analysis, including sequence assembly, pattern searching, gene and protein function prediction, and structure prediction. The text concludes with a section discussing genome evolution and molecular phylogenetics. This timely and cutting-edge text also:
* Presents both the concepts and methodology of comparative genomics
* Reviews the basic principles of genomics and gene expression analysis
* Covers the bioinformatics approaches to comparative analysis
* Discusses analytic methods in proteomics and transcriptomics
* Includes a comprehensive list of Web resources

The authors draw upon their wealth of teaching and research experience to offer a coherent presentation appropriate for students, trainees, researchers, and scientists across the life sciences.

"About this title" may belong to another edition of this title.

Publisher
Wiley-Liss
Publication date
2003
Language
English
ISBN 10 
047139128X
ISBN 13 
9780471391289
Binding
Hardcover
Edition number
1
Number of pages
448

Other Popular Editions of the Same Title

9780471722724: Handbook of Comparative Genomics: Principles and Methodology

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