Approaches to Gene Mapping in Complex Human Diseases - Hardcover

 
9780471171959: Approaches to Gene Mapping in Complex Human Diseases
Hardcover
ISBN 10: 0471171956 ISBN 13: 9780471171959
Publisher: Wiley–Blackwell, 1998

Synopsis

Approaches to Gene Mapping in Complex Human Diseases Edited by Jonathan L. Haines and Margaret A. Pericak-Vance Recent years have seen a tremendous growth in statistical and laboratory methods for genetic mapping -a process by which we discover genes that contribute to heart disease, hypertension, diabetes, asthma, cancer, and other complex genetic disorders not controlled by a single gene. Approaches to Gene Mapping in Complex Human Diseases is the first book devoted to the analysis of such common, inherited diseases. This text helps the reader sort through the plethora of available resources, choose the best methodology for a given problem, and design successful gene mapping projects from the ground up. In eighteen chapters, compiled by two of the leading figures in the field, this book covers a wide range of topics -from the process of selecting families to the testing of candidate genes. It provides indispensable information on: Genetic concepts and statistics pertaining to mapping genetic disease Issues involved in collecting and handling biological samples and data Strategies for generating data in the lab Methods of analysis such as Lod score, Sib-pair, or Affected Relative-Pair Public databases and mapping resources Sources of statistical and genetic information, software, and documentation. Approaches to Gene Mapping in Complex Human Diseases clearly explains concepts and design procedures while keeping technical details to a minimum. For geneticists, clinicians, molecular biologists, epidemiologists, and anyone interested in the pursuit of genes, it provides a solid grounding in the fundamentals and facilitates a firm grasp of the most advanced procedures and techniques available.

"synopsis" may belong to another edition of this title.

From the Back Cover

Approaches to Gene Mapping in Complex Human DiseasesEdited by Jonathan L. Haines and Margaret A. Pericak-VanceRecent years have seen a tremendous growth in statistical and laboratory methods for genetic mapping --a process by which we discover genes that contribute to heart disease, hypertension, diabetes, asthma, cancer, and other complex genetic disorders not controlled by a single gene.Approaches to Gene Mapping in Complex Human Diseases is the first book devoted to the analysis of such common, inherited diseases. This text helps the reader sort through the plethora of available resources, choose the best methodology for a given problem, and design successful gene mapping projects from the ground up. In eighteen chapters, compiled by two of the leading figures in the field, this book covers a wide range of topics --from the process of selecting families to the testing of candidate genes. It provides indispensable information on: *Genetic concepts and statistics pertaining to mapping genetic disease *Issues involved in collecting and handling biological samples and data *Strategies for generating data in the lab *Methods of analysis such as Lod score, Sib-pair, or Affected Relative-Pair *Public databases and mapping resources *Sources of statistical and genetic information, software, and documentation.Approaches to Gene Mapping in Complex Human Diseases clearly explains concepts and design procedures while keeping technical details to a minimum. For geneticists, clinicians, molecular biologists, epidemiologists, and anyone interested in the pursuit of genes, it provides a solid grounding in the fundamentals and facilitates a firm grasp of the most advanced procedures and techniques available.

"About this title" may belong to another edition of this title.

Publisher
Wiley–Blackwell
Publication date
1998
Language
English
ISBN 10 
0471171956
ISBN 13 
9780471171959
Binding
Hardcover
Number of pages
464
Editor
Haines Jonathan L., Pericak–Vance Margaret A.