A Practical Guide to Molecular Cloning By Bernard Perbal Presents detailed procedures for all phases of DNA cloning experiments. Starting with laboratory equipment and safety considerations, this practical guide goes on to describe enzymes, vectors, purification and characterization techniques, genetic mapping, modification of DNA fragments with cohesive termini, ligation, preparation of genomic libraries, sequencing of DNA, and more. 1984 554 pp. Pharmaceutical Calculations, 2nd Ed. By Joel L. Zatz Expanded and updated, this examination of pharmaceutical calculations features a programmed format designed for fast–paced learning and a progression of topics that builds on previous instruction. The second edition of this popular text includes current unit designations and abbreviations, additional material on the alligation technique and infusion calculations, and many new problems. 1981 388 pp. Drug Level Monitoring, Volume 2 Analytical Techniques, Metabolism, and Pharmacokinetics By Emil T. Lin and Wolfgang Sadée The second volume in a series that describes drug level assays in biological fluid. Reviews of the analysis, metabolism and pharmacokinetics of 16 major classes are included. Details are presented on therapeutic drug concentrations in plasma, pharmacokinetic parameters, and a large number of drug assay procedures applicable to biological specimens. All of these subject areas have been carefully combined to render this book a unique reference source, teaching tool, and guide to drug level monitoring. 1985 250 pp.
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Kenneth A. Connors is Professor of Pharmacy at the University of Wisconsin, Madison. He has been appointed a fellow in the Academy of Pharmaceutical Sciences (1972) and in the AAAS (1981). Dr. Connors received his Ph.D. in pharmacy from the University of Wisconsin, Madison in 1959. He is also the author of Reaction Mechanisms in Organic Analytical Chemistry (Wiley–lnterscience, 1973) and co–author of Chemical Stability of Pharmaceuticals (WileyInterscience, 1979).
Beginning with the fundamentals and progressing to more advanced topics, this classic text offers a detailed, systematic treatment of modern analytical chemistry. It provides all the necessary background for understanding most analyses in principle and many in detail. Updated and expanded, this edition emphasizes not only the principles of pharmaceutical analysis, but also the practical applications. It features an expanded section on liquid chromatography along with new chapters on immunoassay, derivative formation, and statistical interpretation of data. Practical learning aids include numerous student laboratory experiments along with more than 250 problems, many with answers given. Incorporating traditional techniques with the most current methods, Dr. Connors offers step–by–step coverage of five major areas: Titemetric Analysis, Physical and Instrumental Methods, Separation Techniques, Elemental Analysis, and Clinical Reactions in Analysis. He also deals with general topics, such as volumetric techniques and calculations and how to use the analytical literature. A Textbook of Pharmaceutical Analysis, 3rd Edition is specifically geared for undergraduate courses in pharmaceutical analysis, but graduate students and professional pharmacists will find it a useful reference. Rigorous yet accessible, it is a valuable tool for practical analyses as well as for understanding such literature as the official compendia, reference works in analysis, and advanced textbooks in analytical chemistry.
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