This timely book illustrates the value of bioinformatics, not simply as a set of tools but rather as a science increasingly essential to navigate and manage the host of information generated by genomics and the availability of completely sequenced genomes. Bioinformatics can be used at all stages of genetics research: to improve study design, to assist in candidate gene identification, to aid data interpretation and management and to shed light on the molecular pathology of disease-causing mutations. Written specifically for geneticists, this book explains the relevance of bioinformatics showing how it may be used to enhance genetic data mining and markedly improve genetic analysis.
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Bioinformatics for Geneticists describes a step by step approach to key bioinformatics and genetic analysis procedures, based upon practical experience gained after many years of direct bioinformatics support for laboratory geneticists. It features detailed case studies of problems and analytical approaches that are specific to the needs of the genetics researcher. The book contains reviews of bioinformatics tools and genetic databases. Each chapter is written to capture the principles of analysis regardless of the tool used, thereby ensuring that the book stays relevant as new data and tools become available. As the first book specifically addressing the informatics requirements of geneticists, Bioinformatics for Geneticists is essential reading for all those engaged in genetic research and should prove indispensable for both the planning and analysis of such studies.
*The book provides in-depth coverage of the underlying principles of both genetic and bioinformatic analysis which should make this book suitable for all students of genetics or bioinformatics.
*The book takes a web-based approach to bioinformatics, suitable for both internet novices and more experienced web users.
*The focus is on public software tools and databases freely available to all.
*The editors and authors bring a broad range of experience from academic and industrial genetics research environments.
*The book is accessible to individuals outside the immediate field of molecular genetics, e.g. statisticians, epidemiologists and physicians who wish to improve their knowledge of bioinformatics and genetics.
*This is currently the only book specifically aimed at the bioinformatics needs and priorities of genetics researchers.
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