Principles and Practice of Skin Toxicology - Hardcover

Hardcover

ISBN 10: 0470511729 ISBN 13: 9780470511725

Publisher: Wiley, 2008

Synopsis

Written by authorities in the field, this book provides a “bottom up” approach to studying skin toxicology. Principles and Practice of Skin Toxicology clearly outlines basic concepts, cites historical and modern references and contains a dictionary for easy reference. The inclusion of global legislation and regulatory aspects on the topic makes this a comprehensive review for every practitioner, clinical researcher in industry and academia, and MSc and PhD student of toxicology.

• Different sections cover skin structure and function, principles and measurement of skin absorption, clinical aspects of dermal toxicity and in vitro alternatives. 
• A section on regulatory and legislative aspects includes case studies from the UK that fulfill European Union and US FDA requirements.
• A glossary provides definitions of technical terms, and the chapters contain an introduction, learning boxes and summary section for ease of use. 
• Includes a chapter on drug delivery through the skin.
• Addresses risk assessment: a key area for the interpretation of skin absorption data that is rarely covered.

About this title

About the Author

Robert Peter Chilcott, Senior Toxicologist, Chemical Hazards and Poisons Division HQ, Health Protection Agency, Chilton, UK.

Shirley Price, Senior Lecturer in Toxicopathology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, UK.

From the Back Cover

Written by experts in the field, Principles and Practice of Skin Toxicology provides a “bottom up” approach to studying skin toxicology. It provides a clear outline of basic concepts, citing both historical and modern references, and contains a glossary of key terms for quick and easy reference.

Arranged in a user friendly and logical sequence, the book covers the five main areas of dermatotoxicology:

• Principles of skin absorption. Explains the factors influencing dermal absorption and associated methods of measurement.
• Methods for assessing skin toxicity. An overview of both in vivo and in vitro approaches to testing, with particular emphasis on the validation and use of alternative test strategies.
• Clinical and occupational skin toxicity. A basic introduction to dermatology and related applications central to understanding dermal exposure to chemicals.
• Regulatory aspects. An overview of national and international legislation governing the safe marketing of pharmaceuticals, cosmetics and industrial chemicals.

This book will be especially useful to scientists who are new to the area of dermal toxicology, as well as practitioners of toxicology, clinical researchers, and researchers in industry and academia.

Arranged in a user friendly and logical sequence, the book covers the five main areas of dermatotoxicology:

• Principles of skin absorption. Explains the factors influencing dermal absorption and associated methods of measurement.
• Methods for assessing skin toxicity. An overview of both in vivo and in vitro approaches to testing, with particular emphasis on the validation and use of alternative test strategies.
• Clinical and occupational skin toxicity. A basic introduction to dermatology and related applications central to understanding dermal exposure to chemicals.
• Regulatory aspects.  An overview of national and international legislation governing the safe marketing of pharmaceuticals, cosmetics and industrial chemicals.

This book will be especially useful to scientists who are new to the area of dermal toxicology, as well as practitioners of toxicology, clinical researchers, and researchers in industry and academia.

Edition details

• Publisher: Wiley
• Publication date: 2008
• Language: English
• ISBN 10: 0470511729
• ISBN 13: 9780470511725
• Binding: Hardcover
• Edition number: 1
• Number of pages: 392
• Editor: Chilcott Robert, Price Shirley