"synopsis" may belong to another edition of this title.
"This book will be certainly a valuable reference source for all those who are interested in antiviral drug discovery. All of the information contained in this text offers a rich scientific support for researchers in academia and industry at any level who are interested in enhancing their knowledge on a very fascinating scientific topic." (ChemMedChem, 2012)
Provides the Foundation Needed to Design Effective HIV-1 Integrase Inhibitors
Around the world, scientists have been working for years with the goal of designing effective HIV-1 integrase inhibitors in the battle against AIDS. This book reviews all their latest research findings on both inhibitor design and the mechanisms of action of HIV-1 integrase. Chapters have been contributed by leading pioneers in the field from North America, Europe, and Asia. These contributions represent not only a thorough review of the current literature, but also the authors' firsthand experience in drug development and design. Coverage includes such topics as:
Integrase mechanism, structure, and function
HIV-1 integrase-DNA interaction
Host factors affecting provirus stability and silencing
Role of metals in HIV-1 integrase inhibitor design
Historic perspectives, challenges, and future opportunities
As the first publication to comprehensively examine HIV-1 integrase, this book is essential reading for anyone involved in inhibitor drug discovery.
Integrates chemical, biochemical, and biological approaches, enabling readers to take full advantage of a promising target enzyme for combating HIV and retroviruses
Illustrates rational drug design for a complex drug target with plenty of step-by-step examples
Addresses drug design issues from a variety of perspectives to help readers understand both the challenges and opportunities of developing a successful HIV-1 integrase inhibitor
This book fills an important gap in the review literature, offering a valuable introduction to the field for scientists who need to collaborate with researchers in several disciplines in order to design drugs that effectively target HIV-1 integrase.
"About this title" may belong to another edition of this title.
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Book Description Condition: New. Seller Inventory # 5160096-n
Book Description Condition: New. Seller Inventory # 5160096-n
Book Description Hardcover. Condition: new. Hardcover. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9780470184745
Book Description HRD. Condition: New. New Book. Shipped from UK. Established seller since 2000. Seller Inventory # FW-9780470184745
Book Description Hardcover. Condition: New. Seller Inventory # 6666-WLY-9780470184745
Book Description Gebunden. Condition: New. Nouri Neamati, PhD, is an Associate Professor of Pharmacology and Pharmaceutical Sciences at the University of Southern California School of Pharmacy. He is the recipient of numerous awards and has published more than 170 peer-reviewed manuscripts, several . Seller Inventory # 5917380
Book Description Condition: New. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Editor(s): Neamati, Nouri. Series Editor(s): Wang, Binghe. Num Pages: 520 pages, Illustrations (some col.). BIC Classification: MJ; MM; PN; PS. Category: (P) Professional & Vocational. Dimension: 284 x 220 x 31. Weight in Grams: 1460. . 2011. 1st Edition. Hardcover. . . . . Seller Inventory # V9780470184745
Book Description Hardcover. Condition: Brand New. 1st edition. 528 pages. 11.25x8.75x1.25 inches. In Stock. Seller Inventory # __0470184744
Book Description Hardcover. Condition: new. Hardcover. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. Seller Inventory # 9780470184745
Book Description Condition: New. This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Editor(s): Neamati, Nouri. Series Editor(s): Wang, Binghe. Num Pages: 520 pages, Illustrations (some col.). BIC Classification: MJ; MM; PN; PS. Category: (P) Professional & Vocational. Dimension: 284 x 220 x 31. Weight in Grams: 1460. . 2011. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland. Seller Inventory # V9780470184745