Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities â€" the ‘nuts and bolts†of cellular information exchange. With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding. An accessible introduction to the complex field of cell signalling Interacts with RasMol software â€" freely downloadable for viewing structures in 3D Includes exercises and clear instructions in the use...
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"Richly illustrated with full-color molecular graphics (created by RasMol, a freeware molecular visualization program), Structure and Function in Cell Signaling provides a clear, engaging introduction to signal transduction. Each of the book's 10 chapters includes tables and charts in color to illustrate signal transduction pathways and genetic relationships between signal transduction molecules. Nelson (Queens Univ. Belfast, UK) provides enough background information to make this complex subject accessible even to beginning students. Readers can easily re-create all of the molecular graphics for themselves in an interactive format by following simple instructions included in the appendix. Signal transduction has applications in all of the biological sciences. Thus, students in cell biology, biochemistry, immunology, molecular genetics, and other life sciences will all find much valuable information in this work. Summing Up Highly recommended. Academic libraries, all levels."(Choice, February 2009)
"From basics to details, this is an elegantly written and carefully edited book. The chapters on cell cycle control and oncogenesis are particularly fascinating and valuable to biomedical research. This is the book to have if you are interested in molecular mechanisms of signal transduction. It is a great introduction to the literature that will be welcomed by students and experts alike." (Doody's, January 2009)
John Nelson, Queen's University, Belfast, UK.
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