Techniques in Free Radical Research (Volume 22) (Laboratory Techniques in Biochemistry and Molecular Biology, Volume 22) - Softcover

Diplock, A.T.; Symons, M.C.R.; Rice-Evans, C.A.

Softcover

ISBN 10: 0444813144 ISBN 13: 9780444813145

Publisher: Elsevier Science, 1991

Synopsis

Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage.

Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used towards the measurement of radicals and radical-mediated damage in chemical systems, in cells and in tissues under the following six headings: a) Footprints of DNA damage, b) Footprints of protein damage, c) Footprints of lipid peroxidation, d) Footprints of antioxidant consumption, e) Footprints via indirect radical assays, and f) Footprints via the availability of transition metal complexes.

About this title

Review

"...every biological scientist interested in free radicals should find this an affordable book well worth having on the laboratory or office bookshelf." --FEBS Letters

Edition details

• Publisher: Elsevier Science
• Publication date: 1991
• Language: English
• ISBN 10: 0444813144
• ISBN 13: 9780444813145
• Binding: Paperback
• Number of pages: 290